http://tdudspace.texicon.in:8080/jspui/handle/123456789/284 2026-04-14T19:50:26Z 2026-04-14T19:50:26Z Aradhya, Bhuvana http://tdudspace.texicon.in:8080/jspui/handle/123456789/547 2024-08-08T11:11:35Z 2024-07-01T00:00:00Z

Title: Comparative analysis of mechanism of anti-diabetic action of Nishakathakadi Kashayam and Varanadi Kashayam Authors: Aradhya, Bhuvana Abstract: Data collection of phytochemicals present in both Nishakathakadi (NK) and Varanadi (VA) formulations and analyzed which phytochemicals are common between the two, which are unique to each formulation. Additionally, classified the phytochemicals in both formulations. Previous in silico studies showed that both formulations target diabetic-associated genes linked to complications like retinopathy, neuropathy, nephropathy, myopathy, wound healing, and vascular issues. It was found out that NK and VA target 13genes which are similar. Using this information, identified and organized the common phytochemicals in both formulations. To understand the different biological effects due to the overlapped and unique genes targeted by NK and VA, gene ontology and enrichment analysis is performed. These analyses highlighted the biological significance of the targeted genes. The information generated from the enrichment analysis will guide future studies. As part of the comparative analysis, lipase inhibition and cell viability (in intestinal cell lines) were also studied.

2024-07-01T00:00:00Z Dipin V M http://tdudspace.texicon.in:8080/jspui/handle/123456789/546 2024-08-08T11:07:44Z 2024-07-01T00:00:00Z

Title: Standardization of Kshamatva Churna: A Nutraceutical Formulation Authors: Dipin V M Abstract: Kshamatva Churna, composed of nine herbal ingredients including Guduchi, Aswagandha and Yastimadhu, has shown potential to support resilience and mitigating respiratory symptoms. The study highlights the challenges encountered with consumption the traditional dosage form of Kshamatva Churna, which inspired to convert into user-friendly nutraceutical forms such as sugar candy, palm jaggery candy, crystals, dip tea bags, and easily soluble powders.

2024-07-01T00:00:00Z Mahambre, Shachi Suvas Prabhu http://tdudspace.texicon.in:8080/jspui/handle/123456789/545 2024-08-08T10:53:31Z 2024-07-01T00:00:00Z

Title: Exploring antiaging and nootropic potential of aromatic essential oils using Caenorhabditis elegans models Authors: Mahambre, Shachi Suvas Prabhu Abstract: In Ayurveda, selected Sugandhi Dravya (aromatic drugs) are traditionally used to treat depression disorders. This study focused on four essential oils Chandana, Karpura, Vacha, and Jatamansi, which were selected on their therapeutic benefits. Utilizing the Caenorhabditis elegans models, we assessed the nootropic and anti-ageing properties of these essential oils. Additionally, we investigated their effects on Ser-1 knockout mutant strain, which is defective in serotonin signalling and serves as a model for depression. Our research examined the overall lifespan, healthspan, fecundity and oxidative stress in these worms

2024-07-01T00:00:00Z Sruthi G http://tdudspace.texicon.in:8080/jspui/handle/123456789/544 2024-08-08T10:49:05Z 2024-07-01T00:00:00Z

Title: Healthcare Utilization and Out-of-Pocket Expenditure Associated with Depression in Adults in Phc Settings of Urban Bhopal - A Cross-Sectional Study Authors: Sruthi G Abstract: The study titled “Healthcare Utilization and Out-of-Pocket Expenditure associated with Depression in Adults in PHC settings of Urban Bhopal. A cross-Sectional Study” addresses the significant research gap in understanding depression-related healthcare costs in urban Bhopal, India. It highlights the absence of localized data on the economic impact of depression, especially in low and middle-income countries (LMICs). The study focuses on healthcare utilization and out-of-pocket expenditures (OOPE) among adults aged 18 years and above with depression, using data collected from households near primary healthcare centers.

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