A Test of the Systems Analysis Underlying the Scientific Theory of Ayurveda’s Tridosha

Abstract

This paper proposes independent scientific evidence for the proposed identification of the doshas and for the systems analysis on which it is based. In particular, it points to coenzyme A, a key component of fatty acid metabolism. Its universal presence in all cells implies that it is an evolutionary invariant ant that the biochemical pathway on which it lies must be exceptionally significant. The systems analysis shows that the pathway connects the cellular functions of energy turnover and energy storage, fundamental to the overall strategy of cell regulation. This, combined with the requirement for the pathway’s close regulation, makes it effectively impossible to replace coenzyme A by a combination of simultaneous mutations or sequence of mutations and it should indeed remain invariant during evolution.