Role of Stim in Post Embryonic Development of Drosophila Melanogaster

Abstract

Calcium (Ca2+), a major secondary messenger, has been shown to play a pivotal role in various phases of an organism’s life cycle (Paudel et al., 2018). This is because it coordinates a diverse spectrum of cellular events in response to external signalling cues; leading to both biochemical and genetic alterations within the cell (Bagur & Hajnóczky, 2017a). The cellular internal environment exhibits robust responsiveness to fluctuations in calcium concentration, ranging from nanomolar to millimolar. The precise spatiotemporal variations in calcium concentration determine the fate of the cell (Bagur & Hajnóczky, 2017a; Clapham, 2007). Any perturbation in these events may lead to developmental defects or may even result in the lethality of the organism (Paudel et al., 2018).