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Please use this identifier to cite or link to this item: http://tdudspace.texicon.in:8080/jspui/handle/123456789/668
Title: Optimized protocol for assay for transposaseaccessible chromatin by sequencing (ATACseq) from Drosophila melanogaster brain tissue
Authors: Dhall, Jasmine Kaur
Kasturacharya, Nandashree
Pandit, Awadhesh
C P, Lakshminarayanan
Keywords: transposase-accessible chromatin
ATAC-seq
Drosophila melanogaster
brain tissue
Issue Date: Jun-2023
Publisher: Cell Press
Abstract: Transposase-accessible chromatin by sequencing (ATAC-seq) has emerged as an advantageous technique to assess chromatin accessibility owing to the robustness of "tagmentation" process and a relatively faster library preparation. A comprehensive ATAC-seq protocol from Drosophilabrain tissue is currently unavailable. Here, we have provided a detailed protocol of ATAC-seq assay from Drosophila brain tissue. Starting from dissection and transposition to amplification of libraries has been elaborated. Furthermore, a robust ATAC-seq analysis pipeline has been presented. The protocol can be easily adapted for other soft tissues.
URI: http://tdudspace.texicon.in:8080/jspui/handle/123456789/668
Appears in Collections:Researcher/Student Publications

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