Please use this identifier to cite or link to this item:
http://tdudspace.texicon.in:8080/jspui/handle/123456789/712| Title: | Sida cordifolia is efficacious in models of Huntington’s disease by reducing ER stress |
| Authors: | Simha, Prasanna K. Godbole, Ashwini Upadhyay, Sanjeev K. |
| Keywords: | Sida cordifolia neurodegeneration Huntington’s disease ER stress ayurveda biology |
| Issue Date: | Mar-2025 |
| Publisher: | Frontiers in Molecular Biosciences |
| Citation: | Simha PK, Mukherjee C, Kumar Gupta V, Bhatia K, Nagar P, ZA AN, Godbole A, Sahu BS and Upadhyay SK (2025) Sida cordifolia is efficacious in models of Huntington’s disease by reducing ER stress. Front. Mol. Biosci. 12:1567932. doi: 10.3389/fmolb.2025.1567932 |
| Abstract: | Neurodegenerative disorders (NDs) are a major class of diseases where modern science has not succeeded in providing solutions to the desired levels. ER stress pathway is implicated in pathophysiology of several neurodegenerative disorders, especially those classified as proteinopathies. Several traditional medicines are used to treat neurodegeneration and Sida cordifolia (SC) is one of the common ingredients in formulations used for treating NDs and neuropathic pain. However, the mode of action is not clear. We studied the effectiveness of SC in Huntington’s Disease (HD) model using Caenorhabditis elegans and mammalian cells. |
| URI: | http://tdudspace.texicon.in:8080/jspui/handle/123456789/712 |
| Appears in Collections: | Faculty Publications |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Sida cordifolia is efficacious in models of Huntington’s disease by reducing ER stress_compressed.pdf Restricted Access | 445.71 kB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.