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http://tdudspace.texicon.in:8080/jspui/handle/123456789/726| Title: | In vitro and in silico analysis proving DPP4 inhibition and diabetes-associated gene network modulation by a polyherbal formulation: Nisakathakadi Kashaya |
| Authors: | Thottappillil, Anjana Kouser, Sania Garawadmath, Soumya Banvi, Pranav Kukkupuni, Subrahmanya Kumar Chethala N., Vishnuprasad |
| Keywords: | DPP4 Docking Molecular dynamics Network pharmacology Diabetes Ayurveda |
| Issue Date: | Oct-2023 |
| Publisher: | Taylor & Francis |
| Citation: | Anjana Thottappillil, Sthitaprajna Sahoo, Abhijnan Chakraborty, Sania Kouser, Vidhya Ravi, Soumya Garawadmath, Pranav Banvi, Subrahmanya Kumar Kukkupuni, S Suma Mohan & Chethala N. Vishnuprasad (08 Nov 2023): In vitro and in silico analysis proving DPP4 inhibition and diabetes-associated gene network modulation by a polyherbal formulation: Nisakathakadi Kashaya, Journal of Biomolecular Structure and Dynamics, DOI: 10.1080/07391102.2023.2276880 |
| Abstract: | Dipeptidyl-peptidase IV (DPP4) inhibitors are an important class of anti-diabetic drugs recognised for their systemic biological actions. Polyherbal preparations like Ayurveda formulations are considered to be ideal sources for discovering novel DPP4 inhibitors owing to their rich phytochemical composition. The current study reports the DPP4 inhibitory potential of a clinically established Ayurvedic anti-diabetic formulation Nisakathakadi Kashaya (NK) using in vitro assay and substantiates it by identifying potential bioactives responsible for DPP4 inhibition using computational biology tools. |
| URI: | http://tdudspace.texicon.in:8080/jspui/handle/123456789/726 |
| Appears in Collections: | Researcher/Student Publications |
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|---|---|---|---|---|
| In vitro and in silico analysis proving DPP4 inhibition and diabetes associated gene network modulation.pdf Restricted Access | 891.97 kB | Adobe PDF | View/Open Request a copy |
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